American scientists have developed a new method of fluorescent bioimidgy, which allows real time to observe the processes in the body, identify the cells of the disease and control the effectiveness of treatment. The description of this method is given in Nature Communications.
The fluorescent bioimiding method is already successfully used for molecular visualization at the laboratory and clinical level, in particular for monitoring of lungs and patients' monitoring and after surgery.
In the traditional fluorescent bioimiging, a fluorescent agent is introduced into the tissue or blood, which binds to specific cells or proteins, and in the light of a certain spectrum, these cells become visible. However, this method requires complex calculations for data processing and image construction.
Scientists at the University of Southern California and Cambridge University have presented a new variant of the method known as the method of extended spectral-coded representation (Seer). This method not only observes the molecules, but also distinguish their colors throughout the spectrum and create full -color images of internal organs.
SEER offers a significant advantage in the form of 2.7 times more clarity of image and performance, 67 times faster, which is achieved through a special algorithm for processing of fluorescent labels. This approach also requires fewer computer memory resources, which is important in large -scale studies.
It is planned to use the Seer method for clinical detection of early stages of lung cancer and studying the effects of pollutants on the body.
